Queen Mary scientists find faulty gene causing rare oesophageal cancer
New medical research in London’s East End has uncovered a gene which plays a key role in developing cancer of the gullet.
Researchers from Queen Mary, University of London, found that a fault in the gene known as RHBDF2 was responsible for oesophageal cancer in anyone carrying a rare, inherited condition called Tylosis—the faulty gene made them highly susceptible to the disease.
“Finding a genetic cause for this aggressive cancer and understanding what that gene is doing is an enormous step forward,” said Prof David Kelsell who led the study at Queen Mary’s.
“Analysing the complex biology which causes a particular cancer means we begin to understand which treatments might be effective and which are unlikely to help.”
Oesophageal cancer affects 8,000 people a year in Britain and is more common than anywhere else in Europe. Survival rates are poor, with only eight per cent living five years after diagnosis.
You may also want to watch:
Scientists have known little about how it develops or what drugs currently available could target the disease, until now.
- 1 The Queen lends her name to Royal London’s emergency Covid wards
- 2 Tribute to 7th Barts Health Trust worker to die of Covid-19
- 3 Airbnb house party violence leaves police officer with broken finger
- 4 Teenager found dead in Victoria Park
- 5 Driver arrested after police 'drugs patrol' stops car in Whitechapel
- 6 'We need laptops for lockdown children to learn from home’ Tower Hamlets mayor urges
- 7 Drug and alcohol abuse by Tower Hamlets parents and children soars
- 8 Have you seen this 52-year-old man missing from Ilford?
- 9 Disgraceful management of the pandemic
- 10 Surplus DLR land released at Bow for new housing to tackle homes shortage